Cyanide antidotes may also dilate the blood vessels to reduce oxygen demand. Metabolic acidosis (a condition in which there is excess acid in the body fluids)Ĭyanide antidotes usually combine with cyanide to form a less toxic product that can be easily excreted from the body.If there is an inadequate clinical response after 30 minutes, administer a second dose of sodium thiosulfate which is half the initial dose.
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